Joseph teaches that the then-future US Civil war would be "the first outbreak of general bloodshed" and would commence at South Carolina.
Instruction, 2 April 1843, as Reported by William Clayton [D&C 130], The Joseph Smith Papers website, accessed August 1, 2024
Once when prest. Joseph was praying earnestly to know concerning the wars which are to preceed the coming of the son of man, he heard a voice proclaim that the first outbreak of general bloodshed would commence at South Carolina— see Revelation