Hearthome City (Japanese: ヨスガシティ Yosuga City) is a city in the Sinnoh region. Hearthome City is the fifth-largest city in the Pokémon world. Hearthome City is home to the Super Contest Hall, where one can take part in the Super Contest, a Gym, the Pokémon Fan Club, and the Poffin House, among other things. A hiker will give the player a Happiny Egg here in Diamond and Pearl and Brilliant Diamond and Shining Pearl. Hearthome City started as a place where people and Pokémon gathered and grew into a center of commerce. It is also a gateway to nearby Solaceon Town and Pastoria City.

Hearthome City is a child-friendly city; there are many families and young mothers living there, some of whom can be seen with prams. Most of the buildings use elevators instead of stairs so that small children and Pokémon can move through the houses. The citizens scrupulously keep their city clean.

In Platinum, the road paving was given an update so it is now all beige. The tree's sprites were changed to match those in Platinum's Eterna Forest. In addition, the appearance of the entrances to Amity Square was modified so that the arch features a Psyduck, a Torchic and a Drifloon, and a Pikachu on its back.